JPEN:早期使用甘油磷酸钠预防高危早产儿早期低磷血症的疗效

2019-03-09 不详 MedSci原创

早期低磷血症在小于1250g的早产儿中很常见。本研究的目的是评估从使用肠外营养的第一天起就补充甘油磷酸钠对低磷血症发生的频率和严重程度的影响。

背景
早期低磷血症在小于1250g的早产儿中很常见。本研究的目的是评估从使用肠外营养的第一天起就补充甘油磷酸钠对低磷血症发生的频率和严重程度的影响。

方法
研究人员将出生体重≤1250g的婴儿前瞻性纳入队列研究,所有患儿均出生于三级保健水平的新生儿重症监护室,并从出生后第一天开始提供甘油磷酸钠。主要观察结果是第一周低磷血症(<4 mg / dL)的发生情况。

结果
本项研究共纳入五十四名新生儿。低磷血症的发生率为29.6%。仅1例患者出现低磷血症<2 mg / dL。8名患者(50%)发现轻度低钾血症。没有观察到高钠血症的病例。低磷血症患者的胎龄明显较低(27.4 vs 28.8周,P = .032 )和较低的z-分数(-1.68 vs -0.47; P = .001)。婴儿间发病率或死亡率没有差异。

结论
从出生第一天开始,就在肠外营养中补充甘油磷酸钠可以显着降低了低磷血症的发生率。

原始出处:

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

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    2019-08-21 feather89

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1727929, encodeId=65611e2792982, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 21 02:33:00 CST 2019, time=2019-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=362633, encodeId=72b9362633eb, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqYPFHuMA3bhYQrHvycmum7IJoCsLK0FP6X56Eoj9PZAECDke8zLCKxZZvk9q7B6rZmPuFgN5YCfw/132, createdBy=00912551888, createdName=12543c13m83暂无昵称, createdTime=Thu Mar 14 11:22:39 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531006, encodeId=77291531006a9, content=<a href='/topic/show?id=e80b26301b6' target=_blank style='color:#2F92EE;'>#低磷血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26301, encryptionId=e80b26301b6, topicName=低磷血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7f312187038, createdName=medscijoin, createdTime=Mon Mar 11 08:33:00 CST 2019, time=2019-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032092, encodeId=4dac1032092df, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sat Mar 09 20:33:00 CST 2019, time=2019-03-09, status=1, ipAttribution=)]
    2019-03-14 12543c13m83暂无昵称

    谢谢分享

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    2019-03-11 medscijoin
  4. [GetPortalCommentsPageByObjectIdResponse(id=1727929, encodeId=65611e2792982, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 21 02:33:00 CST 2019, time=2019-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=362633, encodeId=72b9362633eb, content=谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqYPFHuMA3bhYQrHvycmum7IJoCsLK0FP6X56Eoj9PZAECDke8zLCKxZZvk9q7B6rZmPuFgN5YCfw/132, createdBy=00912551888, createdName=12543c13m83暂无昵称, createdTime=Thu Mar 14 11:22:39 CST 2019, time=2019-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1531006, encodeId=77291531006a9, content=<a href='/topic/show?id=e80b26301b6' target=_blank style='color:#2F92EE;'>#低磷血症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26301, encryptionId=e80b26301b6, topicName=低磷血症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7f312187038, createdName=medscijoin, createdTime=Mon Mar 11 08:33:00 CST 2019, time=2019-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1032092, encodeId=4dac1032092df, content=谢谢梅斯提供这么好的信息,学到很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=内科新手, createdTime=Sat Mar 09 20:33:00 CST 2019, time=2019-03-09, status=1, ipAttribution=)]
    2019-03-09 内科新手

    谢谢梅斯提供这么好的信息,学到很多

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